Palabras clave
Prurigo
Cirrosis hepática biliar Pruritus
Prurigo
Liver cirrhosis
Biliary
Cómo citar
Resumen
El prurito es un síntoma cardinal en Dermatología Clínica, siendo manifestación de enfermedad primaria cutánea, así como, en el diagnóstico y seguimiento de enfermedades de compromiso sistémico. El prurito prolongado, intenso y/o recurrente, puede causar cambios dermatológicos secundarios, tales como la abrasión, la excoriación, el prurigo nodular de Hyde (PNH), la liquenificación y lesiones cicatriciales. Es por esto, que el abordaje del paciente con prurito, debe hacerse de una forma integral, ya que, hasta en un 50% de los casos, puede ser el único síntoma de una enfermedad sistémica y potencialmente seria. La Cirrosis Biliar Primaria (CBP) es una enfermedad gastrointestinal autoinmune, de baja incidencia y prevalencia, que tiene como manifestación inicial el prurito hasta en el 60-80% de los casos, e incluso puede ser uno de los síntomas más precoces. Por esta razón, el dermatólogo debe reconocer sus manifestaciones clínicas, para una aproximación diagnóstica y terapéutica. Se presenta el caso de una paciente de 58 años, con cuadro de prurito crónico y PNH secundario a este, quien había previamente recibido varios tratamientos (incluyendo ciclosporina), sin presentar mejoría, en quien se estudió y se confirmó el diagnóstico de CBP y posteriormente se hizo el manejo pertinente, con mejoría sintomática del prurito y de las manifestaciones cutáneas secundarias.
Citas
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