Palabras clave
Edema macular
Facoemulsificación
Nepafenac
Cirugía de catarata
Inflamación Anti Inflammatory agents
Non steroidal
Macular edema
Phacoemulsification
Nepafenac
Cataract surgery
Inflammation
Cómo citar
Resumen
Objetivos: comparar la inflamación, el espesor retiniano, la agudeza visual mejor corregida (AVCC) y la incidencia de edema macular postcirugía de catarata, en ojos tratados con nepafenac, dexametasona o la combinación de los dos. Métodos: estudio prospectivo, aleatorizado, controlado y ciego para el observador. Se aleatorizaron 147 ojos con catarata para recibir dexametasona 0.1% cada 6 horas por 12 días de forma postoperatoria, nepafenac 0.1% cada 8 horas antes de la cirugía y por 15 días postoperatorios o la combinación de los dos. Los desenlaces medidos fueron miosis intraoperatoria, presión intraocular a la primera y sexta semana, AVCC postoperatoria, volumen macular total, espesor foveal y perifoveal medidos por tomografía óptica coherente, y la presencia o ausencia de edema macular (espesor foveal > 240 micras) en la sexta semana. Resultados: el grupo dexametasona presentó mayor miosis intraoperatoria que el grupo nepafenac (p0.05). Conclusión: los tres esquemas son efectivos y seguros para prevenir la inflamación postoperatoria. El uso de nepafenac conlleva menor miosis intraoperatoria y especialmente como monoterapia, en menor presión intraocular a la primera semana postoperatoria y menor espesor perifoveal.
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