Keywords
Choque séptico
Antibacterianos
Pronóstico Sepsis
Septic shock
Anti-bacterial agents
Prognosis
How to Cite
Abstract
Background: Sepsis is an important cause of ICU mortality and represents a considerable use of resources. National studies are limited. Objective: To describe the clinical course of patients with sepsis in a private polyvalent ICU during a 6-month period. Methodology: Observational, descriptive study. Clinical, demographic, and epidemiologic variables were measured, in addition to length of hospital stay, advanced support, health status, and severity scores, inter alia. A sub-group analysis of 58 patients was done using the 2016 SEPSIS-3 consensus. This was the first local trial characterizing septic patients based on the new international definition. Results: 129 septic patients were included, of which 101 (78%) developed septic shock. The survival rate was 79.8% (n103) with a mortality rate of 20.16% (n26). 28% required inotropy, while 12% required renal therapy. The primary causes were: pulmonary (36%), abdominal (34%), and urinary (13.1%); 36.7% developed multiple organ failure. In 82% cultures were taken and 57% were positive, with 49.61% of
community acquired infections and 50.3% hospital care-associated infections, with no differences in survival (p=0.087). A Glasgow score of >13, less sedation, APACHE<15, no vasopressors needed, or mechanical ventilation, absence of multiple organ failure and lower lactate levels were associated with better survival. Conclusions: In contrast with other studies, the mortality rates were lower. Considering early ICU admission, 24-hour intensivist care, early resuscitation in the ER, rapid response teams and major epidemiological and social factors, all contribute to modify the disease outcomes. Trials designed and developed at the local level are required based on the definition of the third consensus and the prospective administration of SOFAq for early scoring, hence facilitating the early recognition of septic patients.
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