Abstract
Rationale: the behavior of oxygen saturation during sleep in children diagnosed with sleep apnea/hypopnea syndrome (SAHS) has not been sufficiently studied at high altitudes. Objective: To describe the oxygen saturation during wake, sleep and apnea-hypopnea in children under 18 years old with SAHS living at 2640 meters above sea level. Design: cross-sectional study.polysomnographic results were classified as normal or obstructive/central SAHS with or without periodic breathing (PB) and oxygen saturation was registered in wakefulness, during sleep (REM and No REM) and during apnea/hypopnea events. Data analysis was performed using Student’s and chi-square tests. Results: we included 430 children (42% female). In children 1yr, 26,8% had obstructive apnea (p1yr with central apnea had PB (p=0.05). Children >1yr with normal AHI had an awake and sleeping oxygen saturation >90% while those <1yr had 88,8% and 89,6% during NREM and REM, respectively) (p<0.001). All SAHS cases showed a saturation fall as they went from awake state to asleep state (NREM and REM) with peaks of desaturation between 78 and 82%. Conclusions: at 2640 m above sea level, children with SAHS have sleep desaturation. Central apneas are more frequently seen in children under 1yr (71,9%).The PB is a common pattern in children under 1yr and it is associated with significant desaturation.
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