Myocardial perfusion imaging findings with spec isonitriles in patients diagnosed with kawasaki disease at the Colsanitas Clinics in Bogotá

Abstract

Introduction: Kawasaki disease (KD) is an acute multisystem vasculitis of unknown etiology, occurring mainly in infants and small children. One of the most frequent complications are the cardiac manifestations associated with coronary anomalies, including diffuse dilatation and formation of coronary aneurysms that may lead to early acute myocardial infarction and cardiovascular complications. Objective: to describe the Myocardial Perfusion Imaging (MPI) findings with isonitrile using Single Photon Emission Computed Tomography (SPECT) in 14 patients with a clinical diagnosis of Kawasaki disease. Methodology: medical records from the database of the nuclear medicine department of the Reina Sofia Clinic were reviewed from January 2014 through July 2014. The purpose was to collect data from patients referred from the pediatric cardiology outpatient unit to the nuclear medicine department, in order to perform a Myocardial Perfusion with Isonitriles. Results: the sample included medical records and images from 14 patients (57% females). The average age at diagnosis of the KD was 20 months; the time elapsed between the diagnosis and the IgG administration was 3-5 days. In 100% of the patients, the MPI was reported as normal. Conclusion: early diagnosis of Kawasaki Disease and the administration of IgG y within the first 10 days after the onset of symptoms could be associated with the development of less coronary complications. The Myocardial Perfusion with Isonitriles (MPI) trial has been shown to be a valuable non-invasive diagnostic tool for the evaluation and follow-up of these patients.