Prevalence of microalbuminuria in diabetes mellitus type 2 patients

Abstract

Introduction: microalbuminuria is an easy to detect complication in diabetes type 2 patients and is an important predictor of renal and cardiovascular disease. In our environment there are no trials determining the prevalence of microalbuminuria in diabetes Type 2 patients. Methodology: the purpose of this crosscutting trial developed in specialized care is to establish the prevalence of microalbuminuria, evaluating associated risk factors in a group of patients with diabetes mellitus type 2, representative of the Colombian population. 226 patients (56% females and 44% males) were studied, with a mean age of 65 ± 10 years and time of evolution of diabetes of 9.6 ± 7.3 years. At least two separate samples were evaluated, and albumin levels were measured in a separate urine sample. Results: the prevalence of microalbuminuria, macroalbuminuria, and kidney failure was 23.5, 6.2% and 6.2%, respectively. The renal dysfunction was related to a longer duration of the diabetes Chi-square (p = 0,003), with high blood pressure Chi-square (p = 0,008), and chronic kidney failure creatinine >1.2mg/dl Chi-square (p = 0,0001). There are no differences in terms of gender (p = 0, 096) or A1c (p = 0,168). The percentage of patients with adequate diabetes control was 48.2%; adequate HBP control 24.8%; total cholesterol levels, LDL and TG is 53.6%, 30.2% and 42.3%, respectively. Conclusions: the prevalence in this trial is similar to other trials around the world, with emphasis on the association between microalbuminuria and high blood pressure, duration of the disease and creatinine. No relationship was found between the presence of microalbuminuria and diabetes control measured with A1c, probably because of the sample size. A trial using a different design is recommended to establish this association.