Palabras clave
Niños
Pediatría Autoimmune hepatitis
Children pediatrics
Cómo citar
Resumen
La hepatitis autoinmune es una enfermedad inflamatoria crónica del hígado la cual afecta a un grupo de pacientes que pierden su tolerancia inmunológica a los antígenos del hígado. Se caracteriza clínicamente por hipergammaglobulinemia, elevación de enzimas hepáticas, presencia de anticuerpos y cambios histológicos. Esta revisión tiene como objetivo realizar una actualización y ampliar el conocimiento acerca de esta enfermedad en la población pediátrica, con el fin que el médico general, pediatra y gastroenterólogo pediatra sean conscientes de la enfermedad y así puedan sospechar, diagnosticar y realizar un tratamiento oportuno para evitar las complicaciones a corto y largo plazo.
Citas
Liberal R, Grant CR, Mieli-Vergani G, Vergani D. Autoimmune hepatitis: a comprehensive review. J Autoimmun. Elsevier Ltd; 2013 Mar; 41:126-39. https://doi.org/10.1016/j.jaut.2012.11.002
Ferri PM, Ferreira AR, Miranda DM, Simões E Silva AC. Diagnostic criteria for autoimmune hepatitis in children: a challenge for pediatric hepatologists. World J Gastroenterol. 2012 Feb 18]; 18(33):4470-3 https://doi.org/10.3748/wjg.v18.i33.4470
Mieli-Vergani G, Vergani D. Autoimmune hepatitis. Nat Rev Gastroenterol Hepatol . Nature Publishing Group; 2011 Jun; 8(6):320-9. https://doi.org/10.1038/nrgastro.2011.69
Lohse AW, Mieli-Vergani G. Autoimmune hepatitis. J Hepatol. European Association for the Study of the Liver; 2011 Jul; 55(1):171-82. https://doi.org/10.1016/j.jhep.2010.12.012
Della Corte C, Sartorelli MR, Sindoni CD, Girolami E, Giovannelli L, Comparcola D, et al. Autoimmune hepatitis in children: an overview of the disease focusing on current therapies. Eur J Gastroenterol Hepatol. 2012 Jul ;24(7):739-46. https://doi.org/10.1097/MEG.0b013e328353750c
Mieli-Vergani G, Vergani D. Autoimmune hepatitis. Nat Rev Gastroenterol Hepatol . Nature Publishing Group; 2011 Jun; 8(6):320-9. https://doi.org/10.1038/nrgastro.2011.69
Della Corte C, Sartorelli MR, Sindoni CD, Girolami E, Giovannelli L, Comparcola D, et al. Autoimmune hepatitis in children: an overview of the disease focusing on current therapies. Eur J Gastroenterol Hepatol. 2012 Jul ;24(7):739-46 https://doi.org/10.1097/MEG.0b013e328353750c
Roberts E A. Autoimmune hepatitis from the paediatric perspective. Liver . 2011 Nov ;31(10):1424-31. https://doi.org/10.1111/j.1478-3231.2011.02603.x
Mieli-Vergani G, Vergani D. Autoimmune hepatitis. Nat Rev Gastroenterol Hepatol . Nature Publishing Group; 2011 Jun; 8(6):320-9. https://doi.org/10.1038/nrgastro.2011.69
Mieli-Vergani G, Vergani D. Autoimmune hepatitis. Nat Rev Gastroenterol Hepatol . Nature Publishing Group; 2011 Jun; 8(6):320-9. https://doi.org/10.1038/nrgastro.2011.69
Liberal R, Grant CR, Mieli-Vergani G, Vergani D. Autoimmune hepatitis: a comprehensive review. J Autoimmun. Elsevier Ltd; 2013 Mar; 41:126-39. https://doi.org/10.1016/j.jaut.2012.11.002
Vergani D, Mieli-Vergani G. Cutting edge issues in autoimmune hepatitis. Clin Rev Allergy Immunol. 2012 Jun ;42(3):309-21. https://doi.org/10.1007/s12016-010-8236-9
Lohse AW, Mieli-Vergani G. Autoimmune hepatitis. J Hepatol. European Association for the Study of the Liver; 2011 Jul; 55(1):171-82. https://doi.org/10.1016/j.jhep.2010.12.012
Mieli-Vergani G, Vergani D. Paediatric autoimmune liver disease. Arch Dis Child. 2013 Dec];98(12):1012-7. https://doi.org/10.1136/archdischild-2013-303848
Mieli-Vergani G, Vergani D. Paediatric autoimmune liver disease. Arch Dis Child. 2013 Dec];98(12):1012-7. https://doi.org/10.1136/archdischild-2013-303848
Lohse AW, Mieli-Vergani G. Autoimmune hepatitis. J Hepatol. European Association for the Study of the Liver; 2011 Jul; 55(1):171-82. https://doi.org/10.1016/j.jhep.2010.12.012
Liberal R, Grant CR, Mieli-Vergani G, Vergani D. Autoimmune hepatitis: a comprehensive review. J Autoimmun. Elsevier Ltd; 2013 Mar; 41:126-39. https://doi.org/10.1016/j.jaut.2012.11.002
Mieli-Vergani G, Vergani D. Paediatric autoimmune liver disease. Arch Dis Child. 2013 Dec];98(12):1012-7. https://doi.org/10.1136/archdischild-2013-303848
Mieli-Vergani G, Vergani D. Paediatric autoimmune liver disease. Arch Dis Child. 2013 Dec];98(12):1012-7. https://doi.org/10.1136/archdischild-2013-303848
Della Corte C, Sartorelli MR, Sindoni CD, Girolami E, Giovannelli L, Comparcola D, et al. Autoimmune hepatitis in children: an overview of the disease focusing on current therapies. Eur J Gastroenterol Hepatol. 2012 Jul ;24(7):739-46. https://doi.org/10.1097/MEG.0b013e328353750c
Della Corte C, Sartorelli MR, Sindoni CD, Girolami E, Giovannelli L, Comparcola D, et al. Autoimmune hepatitis in children: an overview of the disease focusing on current therapies. Eur J Gastroenterol Hepatol. 2012 Jul ;24(7):739-46 https://doi.org/10.1097/MEG.0b013e328353750c
Della Corte C, Sartorelli MR, Sindoni CD, Girolami E, Giovannelli L, Comparcola D, et al. Autoimmune hepatitis in children: an overview of the disease focusing on current therapies. Eur J Gastroenterol Hepatol. 2012 Jul ;24(7):739-46 https://doi.org/10.1097/MEG.0b013e328353750c
Mieli-Vergani G, Vergani D. Paediatric autoimmune liver disease. Arch Dis Child. 2013 Dec];98(12):1012-7. https://doi.org/10.1136/archdischild-2013-303848
Mieli-Vergani G, Vergani D. Paediatric autoimmune liver disease. Arch Dis Child. 2013 Dec];98(12):1012-7. https://doi.org/10.1136/archdischild-2013-303848
Floreani A, Liberal R, Vergani D, Mieli-Vergani G. Autoimmune hepatitis: Contrasts and comparisons in children and adults - a comprehensive review. J Autoimmun. Elsevier Ltd; 2013 Oct;46:7-16. https://doi.org/10.1016/j.jaut.2013.08.004
Floreani A, Liberal R, Vergani D, Mieli-Vergani G. Autoimmune hepatitis: Contrasts and comparisons in children and adults - a comprehensive review. J Autoimmun. Elsevier Ltd; 2013 Oct;46:7-16." https://doi.org/10.1016/j.jaut.2013.08.004