Keywords
Esclerosis Sistémica
Cirrosis Hepática Biliar
Hemorragia Gastrointestinal Hepatitis, Autoimmune
Scleroderma
Systemic
Liver Cirrhosis
Biliary
Gastrointestinal Hemorrhage
How to Cite
Abstract
Autoimmune hepatitis is a disease characterized by chronic inflammation of predominantly periportal hepatocellular tissue (interphase hepatitis) with progressive damage, mainly affecting young women of unknown aetiology. It may present asymptomatically as acute hepatitis or even as liver cirrhosis, being rare its occurrence in combination with other autoimmune diseases such as systemic sclerosis; which is more commonly associated with primary biliary cirrhosis. This article presents the case of a 68-year-old female patient with a history of gastric angiectasis, with a recent diagnosis of systemic sclerosis, without pharmacological management; with major gastrointestinal hemorrhage in which there are evidence of indirect signs of portal hypertension with positive anti-smooth muscle antibodies, associated with the presence of positive anti-nuclear antibodies with anticentromere pattern, making the diagnosis of autoimmune hepatitis. Having relevance in the prognosis, due to the good response of this disease to the early use of steroids to prevent progression to liver cirrhosis and being important in the differential diagnosis of gastrointestinal hemorrhage and recognizing diagnostic alternatives.
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