Keywords
Insuficiencia suprarrenal
Alacrimia
Síndrome de Allgrove
Reporte de caso Esophageal Achalasia
Adrenal Insufficiency
Lacrimal Apparatus Diseases
Allgrove Syndrome
Case report
How to Cite
Abstract
Allgrove Syndrome is an orphan disease with an autosomal recessive inheritance pattern distinguished by the triad of suprarenal insufficiency, achalasia and alacrimia. We describe the case of a previously healthy male preschooler who was admitted to the emergency department of a tertiary care center in poor general status. The patient completed a 25-day hospital stay in which he presented multiple cardiorespiratory arrests, aspiration pneumonia, symptomatic hypoglycemia and a poor response to corticosteroids which gave rise to a suspicion of a metabolic disease. In the outpatient pediatric endocrinology clinic, additional features were noted: generalized skin hyperchromia, alacrimia, and inadequate weight and height gain in the absence of gastroesophageal reflux or achalasia. Allgrove syndrome is an illness with a broad spectrum of manifestations which should be considered despite the absence of the usual triad.
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